Date of Award
January 2023
Document Type
Open Access Thesis
Degree Name
Master of Public Health (MPH)
Department
School of Public Health
First Advisor
Michael S. Leapman
Abstract
Introduction: Given the considerable cultural diversity within the Asian population, numerous factors can significantly impact health status and management. Objective: This study examined the differences in demographic characteristics, clinical characteristics, and treatment status among each Asian American patient with PCa compared to non-Hispanic White and non-Hispanic Black patients by analyzing PCa dataset from National Cancer Database (NCDB) 2004-2020 data. Methods: Patients (n=860,669) with localized PCa diagnosed between 2004 and 2020 who identified as White, Black, Chinese, Japanese, Filipino, Korean, Vietnamese, Asian Indian, or Pakistani within NCDB were extracted and stratified by risk level: low-risk and intermediate/high-risk. The effect of racial group on the mode of initial clinical management was examined using five multivariate logistic regression models. The odds ratios were converted to relative risks. Results: Among low-risk patients, Vietnamese (RR=1.38; 95%CI=1.14-1.63), Chinese (RR=1.30; 95%CI=1.16-1.43), and South Asian (RR=1.23; 95%CI=1.11-1.34) identity was associated with increased use of non-definitive treatment options compared to non-Hispanic White patients. Among intermediate or high-risk patients, Japanese patients (RR=1.09; 95% CI= 1.06-1.13) and Chinese (RR=1.04; 95% CI=1.01-1.07) identity was associated with increased use of definitive treatment options compared to non-Hispanic White; whereas 9% decrease was observed in non-Hispanic Black patients (RR=0.91; 95% CI=0.90-0.92) compared to non-Hispanic White. Conclusions: This study identified notable differences in demographic and clinical characteristics at the time of prostate cancer diagnosis, as well as variations in clinical management. Despite these differences in demographic and clinical characteristics, patients with intermediate and high-risk prostate cancer exhibited minimal variability in their treatment status.
Recommended Citation
Jeong, Farah, "Prostate Cancer Clinical Characteristics And Treatment Among Asian-American Persons In The United States: An Analysis Of The National Cancer Database 2004-2020" (2023). Public Health Theses. 2273.
https://elischolar.library.yale.edu/ysphtdl/2273
This Article is Open Access
Comments
This is an Open Access Thesis.