"Cost-Effectiveness Of Multidisciplinary Management And Exercise Traini" by Anji Yi

Date of Award

January 2016

Document Type

Open Access Thesis

Degree Name

Master of Public Health (MPH)

Department

School of Public Health

First Advisor

Shiyi Wang

Abstract

Background: Multidisciplinary management program (MMP) or exercise training program (ETP) is cost-effective in treating heart failure patients compared with usual care (UC), but no comparison across these three strategies has been made.

Objective: To estimate and compare the cost-effectiveness of MMP, ETP, or UC.

Design: Cohort simulations using a Markov model.

Data Sources: Derived from literature.

Participants: Heart failure (HF) patients aged 56-80 years old.

Time horizon: 10 years.

Intervention: UC, MMP (including disease education and continuous social and psychological support) and ETP (including exercise training and the basic support in MMP).

Outcome Measures: Life-year saved, lifetime costs, and incremental cost-effectiveness ratio (ICER) as measured by cost per life-year saved.

Results of Base-Case Analysis: UC yielded 6.75 life-years saved, MMP 7.12 life-years saved, and ETP 7.93 life-years saved. The associated costs were $10,694, $12,007, and $37,635, respectively. The ICERs were $3,535 per life-year saved in MMP vs. UC, and $31,624 per life-year saved in ETP vs. MMP.

Results of Sensitivity Analysis: The ICERs ranged from $1,307 to $4,743 per life-year saved in MMP vs. UC, and from $16,043 to $42,397 per life-year saved in ETP vs. MMP.

Limitation: No trials have directly compared MMP with ETP; different sources of input data.

Conclusion: In patients with heart failure, MMP and ETP appear to be cost-effective.

Comments

This is an Open Access Thesis.

Open Access

This Article is Open Access

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