Diet and Strength Training Interventions to Decrease Insulin Resistance in Polycystic Ovary Syndrome
Date of Award
4-1-2021
Document Type
Thesis
Degree Name
Master of Medical Science (MMSc)
First Advisor
Pinar Kodaman, MD, PhD
Abstract
Polycystic ovary syndrome is the most common endocrinopathy in females of reproductive age, affecting around 5-10% of women worldwide. While the exact etiology of polycystic ovary syndrome is unknown, insulin resistance is present in a large percentage of affected women. Lifestyle modifications including diet and exercise are the first-line therapy recommended to patients to help manage insulin resistance. However, there is no clear consensus whether exercise alone or in combination with diet offers the greatest reduction in insulin resistance. In this study, we will assess the effect of strength training, low-carbohydrate diet, or a combination approach in women with polycystic ovary syndrome. Specifically, we will use a randomized controlled trial to measure mean changes in homeostatic model assessment of insulin resistance before and after intervention. This work will help providers to better advise this population on management of insulin resistance to prevent future cardiometabolic sequelae.
Recommended Citation
Hartoonian, Ariana, "Diet and Strength Training Interventions to Decrease Insulin Resistance in Polycystic Ovary Syndrome" (2021). Yale School of Medicine Physician Associate Program Theses. 86.
https://elischolar.library.yale.edu/ysmpa_theses/86