Date of Award

Spring 4-17-2025

Document Type

Thesis

Degree Name

Master of Medical Science (MMSc)

First Advisor

Ebony Dix, MD

Abstract

Chronic tinnitus, the persistent perception of sound without an external source, affects approximately 14% of the global population and can significantly impair quality of life. Emerging evidence suggests a possible link between tinnitus and cognitive decline, but the independent contribution of chronic non-pulsatile tinnitus to cognitive decline remains unclear, particularly in younger and middle-aged adults. Prior studies often focus on older populations, use subjective outcome measures, and inadequately control for confounding variables. This retrospective cohort study will use electronic medical records to examine whether adults aged 30–65 with chronic non-pulsatile tinnitus experience a greater rate of cognitive decline, as measured by Montreal Cognitive Assessment scores, compared to individuals without tinnitus. Models will adjust for age, sex, hearing loss, and comorbid conditions. Secondary outcomes are the incidence of mild cognitive impairment and dementia. Findings may inform screening and early intervention strategies in this at-risk population.

Comments

This is an open access thesis.

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