Topiramate for Weight Loss in Adults with Obesity and Loss of Control Eating after Bariatric Surgery
Date of Award
3-25-2022
Document Type
Open Access Thesis
Degree Name
Master of Medical Science (MMSc)
First Advisor
Valentina Ivezaj, PhD
Abstract
Diagnostic criteria for binge eating disorder may preclude a diagnosis in post-bariatric surgery patients because they require consumption of abnormally large quantities. Loss of control eating is considered the salient feature of binge eating disorder in some eating disorder literature, and some of the field is moving towards excluding the quantity of food criterion. Loss of control eating is associated with poorer weight outcomes post-surgery. Topiramate, an anticonvulsant, has been shown to improve weight outcomes in patients with binge eating disorder after surgery, therefore its evaluation in patients with loss of control eating and obesity post-surgery is warranted. We aim to identify whether topiramate increases weight loss and reduces loss of control eating in patients with obesity and loss of control eating after bariatric surgery via a randomized, double-blind, placebo-controlled trial. This study will enhance our understanding of topiramate for weight loss and loss of control eating in this population.
Recommended Citation
Faxon, Amanda, "Topiramate for Weight Loss in Adults with Obesity and Loss of Control Eating after Bariatric Surgery" (2022). Yale School of Medicine Physician Associate Program Theses. 123.
https://elischolar.library.yale.edu/ysmpa_theses/123
