Starting with the Yale School of Medicine (YSM) graduating class of 2002, the Cushing/Whitney Medical Library and YSM Office of Student Research have collaborated on the Yale Medicine Thesis Digital Library (YMTDL) project, publishing the digitized full text of medical student theses on the web as a valuable byproduct of Yale student research efforts. The digital thesis deposit has been a graduation requirement since 2006. Starting in 2012, alumni of the Yale School of Medicine were invited to participate in the YMTDL project by granting scanning and hosting permission to the Cushing/Whitney Medical Library, which digitized the Library’s print copy of their thesis or dissertation. A grant from the Arcadia Fund in 2017 provided the means for digitizing over 1,000 additional theses. IF YOU ARE A MEMBER OF THE YALE COMMUNITY AND NEED ACCESS TO A THESIS RESTRICTED TO THE YALE NETWORK, PLEASE MAKE SURE YOUR VPN (VIRTUAL PRIVATE NETWORK) IS ON.

If you are interested in having your thesis digitized and made part of this collection, please complete the form. Feel free to send questions to Melissa Grafe at

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Theses/Dissertations from 1988

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Identification, characterization, and purification of a 65,000 dalton protein in rat brain that is photolabeled by nitro-containing benzodiazepines, Allen Clarke Bowling

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Workers' health in Connecticut : an historical analysis of the Uretek outbreak, David B. Cowan

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Human immunodeficiency virus antibodies and antigen in infants born to seropopositive mothers, Laura M. Dember

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Prediction of adult height in children with growth disorders, Irene J. Freeman

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A study of the regeneration of olfactory neuron populations in Rana pipiens, David Allen Galbraith

Interferon action, Mariano Agustín García-Blanco

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Interferon Action: A. Studies of the Effect of Interferons on SV40 Replication. B. Studies of the 2'-5' A System, Mariano Agustín García-Blanco

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An effective new prognostic staging system for acquired immunodeficiency syndrome (AIDS), Amy Caroline Justice

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Insulin resistance and hyperinsulinemia precede insulin deficiency in hypertransfused patients with thalassemia major, Peter Alexander Merkel

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Migraine and psychopathology : an analysis by migraine subtype, Geraldine Teresa Mogavero

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HIV testing and informed consent : a study of physician behavior, John Robert Nienow

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Successful immunotherapy to malignant cells with monoclonal antibody to suppressor T cells, Andrės Felipe Rodriguez

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Afferent connections to the prefrontal cortex of the cat : differential fronto-limbic connectivity and manifestations of kindled epileptic foci, Geraldine Skuches Ruffa

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MU : a domain-independent case-based expert system, Mitchell Jay Sklar

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Hemodynamic and metabolic assessment of isolated canine hearts following twenty-four hour preservation in intracellular-type fluid, Steven Brent Slovic

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Characterization of and MYC expression in a HL-60 mutant resistant to DMSO induced differentiation, Walter Michael Stadler

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Heterogeneity of function in human CD4-8-T-cell clones from the periphery, Lisa Ann Straus

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Alteration of the Adenylate cyclase System in Specific Regions of Brain Infected with Creutzfeldt-Jakob Disease, Susan Valley

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Inhibition of CA 125, a Novel High Molecular Weight Glycoprotein Expressed by an Ovarian Carcinoma Cell Line, OVCA 433, is Related to Glucocorticoid Effects of Altered Cell Growth, Morphology, and Growth Pattern, Ellen Michele Weinstein

Theses/Dissertations from 1987

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An investigation of novel flourescent antimetabolites as potential molecular probes in neoplastic cells, Jeffrey Samuel Barkin

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The relationship between myocardial blood flow reduction and heterogeneity of ischemic injury : following experimental coronary artery occlusion in the canine model, Mark Ian Block

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Computer aided evaluation of early neoplasms, Ian Ainsworth Cook

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Echocardiographic study of myocardial performance after exercise in type I diabetes mellitus, Robert R. Englander

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The regulation of tyrosine phosphorylation during the differentiation of a human leukemia, David Alan Frank

The regulation of tyrosine phosphorylation during the differentiation of a human leukemia, David Alan Frank

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The representation of childbirth in the literary works of four physician/authors of the late-nineteenth and twentieth centuries, Patricia Hellman Gibbs

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Mutagenesis and DNA Repair in Mammalian Cells, Peter M. Glazer

Mutagenesis and DNA Repair in Mammalian Cells, Peter M. Glazer

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Autocrine growth regulation of a cloned murine T helper cell line, Jay Bruce Horowitz

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Pseudomonas cepacia colonization in cystic fibrosis : mortality, predictors of poor outcome, and effect on pulmonary function, Linda Orkin Lewin

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Structural homology of the GABAa/benzodiazepine receptor as demonstrated by monoclonal antibodies and limited proteolysis, Robert Thomas Malison

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Deciding for others : rights and responsiblities in medical ethics, Patricia Mary Powell

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The rearrangement of the immunoglobulin and T-cell receptor genes in chronic myelogenous leukemia, Tarik Mustafa Ramahi

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Effects of calmodulin antagonists on ultraviolet induced cytotoxicity in leukemic cells, Seth Allan Rosenthal

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The treatment of peripheral nerve injuries with cyopreserved autografts : a functional, histological, and biochemical evaluation of the role of cryopreservation in the rat model, Patrick Alan Ruwe

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Clonidine and naltrexone : rapid treatment of opioid withdrawal in the outpatient setting, Eugenia Marie Vining

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A retrospective comparison of tumor recurrence and patient survival after treatment with preoperative radiation therapy and surgery, or surgery and postoperative radiation therapy for squamous cell carcinoma of the pyriform sinus and hypopharynx, Jesse George Wardlow Jr.

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The role of cyclosporine in liver disease after renal transplantation, Terry J. Watnick

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Influence of verapamil on total and regional intravascular volume in the dog, Barry S. Weinstock

Theses/Dissertations from 1986

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The mortality of sepsis in a portal hypertensive rat model, Margaret N. Alexander

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Characterization of calmodulin from C₆ astrocytoma cells and rat cerebrum, Jay Alan Gates

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Patient understanding of commonly used medical vocabulary, Richard D. Gibbs

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The role of left atrial chamber size as assessed by echocardiography in determining thromboembolic complications of atrial fibrillation, Cynthia Ann Hall

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Thallium-201 myocardial scintigraphy in the left bundle branch block patient : the importance of left ventricular size, Jacqueline Celeste Hodge

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The effect of protons on phototransduction in the rod outer segment of Bufo marinas, Young S. Kim

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Permeability of the posterior lens capsule in vitro and in vivo, Betty Rae Klein

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Penetration of spinally administered opioids into the lumber spinal cord of cats : an autoradiographic study, Joe Wayne Kurosu

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Deiodination of thyroxine by two NADP-dependent rat liver microsomal deiodinase activities, Benjamin D. Li

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Immunologic infertility and in vitro fertilization/embryo transfer (IVF/ET) : the clinical significance of antisperm antibodies, Stacey Lee Mandelbaum

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Multiple sclerosis : an analysis of T-cell subsets in CNS plaques with attention to plaque borders, Kimberli Etta McCallum

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The transcription and historical analysis of an anonymous physician's handbook dating to the year 1720, Michael David Miller

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The effects of desferrioxamine iron chelation therapy in hypertransfused beta-thalassemia patients, Gail Elizabeth Mizner

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Central nervous system regeneration : survival of retinal ganglion cells and optic nerve in mouse following axotomy and grafting, Matthew R. Moore

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The effects of long-term abstinence on biochemical and hematologic markers for alcoholism, Lynne Valencia Perry

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Predictive factors for bacteremia in outpatient adults, Allen Arthur Ries

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The effect of anti-glycophorin A monoclonal antibodies and FAB fragments on Plasmodium falciparum erythrocyte invasion in vitro, Stephen Joel Roth

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Morbidity, mortality, and graft function in renal transplant recipients : a comparison of the effects of cyclosporine versus azathioprine, Michael Scott Sherman

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Dietary protein and growth in malnourished children, Andrew W. Steele

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Temporal phenomenology of tics in Tourette's syndrome, Paul Princeton Wang

Gene expression during the latent and replicative states of the Epstein-Barr virus, Ronald John Weigel

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Gene expression during the latent and replicative states of the Epstein-Barr virus, Ronald John Weigel

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The effects of a phosphodiesterase inhibitor on intraocular pressure and ciliary process cyclic nucleotide levels in rabbits, Julia Arlene Whiteside

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Some physical characteristics of an adenylate cyclase-stimulating factor(s) associated with humoral hypercalcemia of malignancy, John Joseph Wysolmerski

Theses/Dissertations from 1985

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Effects of antipsychotics on the TRH test in schizophrenic and schizoaffective patients, David M. Alwin

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The fragile X syndrome and infantile autism: a prevalence study, Brian Herb Annex

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Small cell cancer of the lung : an initial evaluation of the Yale treatment protocol, David Jonathan Birnkrant

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Calcium-gonadotropin interaction and their regulation of adenylate cyclase in rat luteal membranes, Alice Sut Chi

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The effects of estrogen on glutamic acid decarboxylase (GAD)- containing neurons in the arcuate nucleus and medial preoptic area of the rat : an electron microscopic immunocytochemical study, Carol F. Farver

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Evaluation of revised criteria for the DSM-III substance use disorders diagnoses, Guy Fish

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Thromboembolic stroke in a young stroke population : clinical characteristics and predictors of short-term stroke outcome, Guy William Fried

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Studies in the neurophysiology of two identified populations of cells and their common synapse in Aplysia californica, William Davis Gaillard

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An evaluation of a hospital-based program for the prediction and prevention of child abuse and neglect, Richard Bruce Garber

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Effects of calcium channel blockade on catecholamine cardiomypopathy, Virginia Shau Huang

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Premeditated enzyme inactivation : the development of mechanism-based irreversible inhibitors of glyoxalase I as potential anti-cancer agents, Stuart Neal Isaacs

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The transmission and natural incubation period of Kuru in three clusters of patients in Papua, New Guinea, Robert Klitzman

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The clinical significance of early radiographic pathology in an asbestos exposed population, Susan Abigail Korrick

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The combined use of Tc-99m-phosphate and Ga-67-citrate imaging in the diagnosis of acute osteomyelitis in children, Jonathan Stuart Lewin

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Keratinocytes produce a PTH-sensitive adenylate cyclase-stimulating factor, John Jerome Merendino Jr.

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Tamoxifen - 5-fluorouracil synergy in human breast cancer cell lines : correlating in vitro synergy with the current estrogen receptor model, Brent Roderick Moelleken

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Improved detection of human breast lesions following experimental training II : a medical student replication, Leslye Carol Pennypacker

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Na and Cl fluxes, and effects of pharmacological agents on the short-circuit current of the isolated rabbit iris-ciliary body, Samuel Richard Pesin

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Health care in the two Germanys : a comparison with emphasis on maternal and infant health care, Anne Carol Regenstein

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Evidence for the involvement of calcium as a second messenger in the secretion of acid, pepsinogen and intrinsic factor from rabbit isolated gastric glands, John R. Roberts

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Exercise induced bronchospasm and the effect of ascorbic acid : a study of the possible role of prostaglandins, Greg A. Sachs

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The effect of a simulated high altitude environment on the morphology of rabbit corneal endothelium, Reginald J. Sanders

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Differentiated microdomains on the luminal surface of the endothelia of murine diaphragm microvessels, Fred E. Santoro

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Hydrocortisone induces aortic rupture in inbred blotchy mice : implications for abdominal aortic aneurysmal disease in humans, Edward Bruce Savage

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Woodshedding : a phase in recovery from psychosis, Joshua David Sparrow

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A clinical trial of clonidine and naltrexone for the outpatient treatment of heroin withdrawal, Mark David Topazian