Date of Award


Document Type

Open Access Thesis

Degree Name

Master of Medical Science (MMSc)

First Advisor

Catherine Yeckel, PhD


Peripheral artery disease impacts greater than 200 million people worldwide and is the third leading cause of atherosclerotic vascular morbidity. The early stages of the disease are ideally treated behaviorally with exercise. However, there is poor exercise adherence due to fear of pain, poor perceived control over the disease, low motivation, and lack of education surrounding the diagnosis. Imaging has been used to change exercise behaviors among patients with other diseases, such as coronary artery disease. This study will test whether allowing participants to see ultrasound images of their vasculature in response to exercise-associated claudication pain will increase adherence to 12 weeks of at-home exercise. We hypothesize that using imaging to create a personalized pain-function scale during the clinical workup will improve patient exercise adherence and thus increase claudication onset time during exercise. If effective, this approach may prove to be instrumental to slowing the progression of peripheral artery disease.

Available for download on Thursday, December 09, 2021

Open Access

This Article is Open Access