Date of Award


Document Type

Open Access Thesis

Degree Name

Master of Medical Science (MMSc)

First Advisor

Mert Ozan Bahtiyar, MD


Preterm birth is one of the most common causes of neonatal morbidity and mortality. The incidence of preterm birth can be reduced by treatment with vaginal progesterone or cervical pessary. However, no studies have supported a treatment regimen that can reduce preterm birth in twin pregnancies. In this study, we will examine whether a combination therapy of vaginal progesterone and cervical pessary can reduce preterm birth in women with dichorionic-diamniotic twin gestations. We will enroll pregnant women with dichorionic-diamniotic twins at 11-14 weeks’ gestation from a local hospital in a randomized control trial. This novel approach may help establish a new management option for twin pregnancies and significantly decrease the morbidity and mortality that affects them.

Open Access

This Article is Open Access