A Study of the Ultracentrifugal Patterns and the Lipid Phosphorus and Cholesterol Levels of Human Sera

William Robert Adams, Yale


The purpose of this paper is to present data correlating three components of human serum: cholesterol, Sf 10-30 molecules, and lipid phosphorus. Three considerations rendered such a study worthwhile: first, the exclusive nature of the work that has been done relating Sf 10-30 molecules to cholesterol made repetition in a different laboratory desirable; second, there are not as yet any published reports concerning the relation of phospholipid levels to the large lipoproteins; and, third, the fact that Gofman relies in part on his studies of rabbit atherosclerosis (which may not be comparable to the human disease) in arriving at his conclusions emphasizes the need for further data on humans.