Disparities In Clinical Trial Representation: Bioethical & Human Rights Violations Against The Global Burden Of Disease And Gender Equity

Author

Kaustubha ReddyFollow

Date of Award

January 2025

Document Type

Open Access Thesis

Degree Name

Master of Public Health (MPH)

Department

School of Public Health

First Advisor

Alice Miller

Second Advisor

Jennifer Miller

Abstract

This investigative thesis seeks to contribute to the understanding of how disparities in the planning, design, and placement of clinical trials perpetuate global health inequities. It will analyze the misalignment between the global burden of disease and research priorities, examining the systemic factors that determine which diseases are prioritized for trials. It will highlight the bioethical and human rights implications of gender exclusion, particularly the underrepresentation of women with HIV, in clinical research. By addressing both the upstream determinants of clinical trial planning and the downstream consequences of exclusionary practices, this work offers a comprehensive critique of the structural inequities in global health research – both historically and in light of the shifting U.S. policy landscape post-January 20, 2025.

Comments

This is an Open Access Thesis.

Recommended Citation

Reddy, Kaustubha, "Disparities In Clinical Trial Representation: Bioethical & Human Rights Violations Against The Global Burden Of Disease And Gender Equity" (2025). Public Health Theses. 2546.
https://elischolar.library.yale.edu/ysphtdl/2546