Date of Award


Document Type

Open Access Thesis

Degree Name

Master of Medical Science (MMSc)

First Advisor

Matthew Grossman, MD


Neonatal abstinence syndrome is a constellation of symptoms that include high pitched crying and irritability resulting from abrupt postnatal cessation of opioid exposure. Maternal recorded song reduces crying duration in preterm and full-term infants. However, the effect of maternal recorded song on crying duration in affected infants is unknown. In this prospective single-blind randomized control trial, we compare the effect of maternal recorded song and ambient noise in reducing crying duration in infants with neonatal abstinence syndrome. We hypothesize that exposure to maternal recorded song will result in a significant difference in mean duration of crying compared to ambient noise in neonates with neonatal abstinence syndrome. The use of maternal recorded song may reduce neonatal crying among all infants. Ultimately, this study will contribute to non-pharmacological management of infants with neonatal abstinence syndrome.

Available for download on Thursday, June 01, 2023

Open Access

This Article is Open Access