Date of Award
Open Access Thesis
Master of Medical Science (MMSc)
Christopher L. Moore, MD
Inpatient mortality for hemodynamically stable patients with pulmonary embolism (PE) averages 5-10%. Tricuspid annular plane systolic excursion (TAPSE), a reliable and reproducible measure of right ventricular (RV) dysfunction has been shown to identify patients with worse prognosis in the cardiology literature, but prognostic utility of TAPSE using point-of-care echocardiogram (FOCUS) in the emergency department (ED) population is sparse. We propose that in a prospective cohort of patients with confirmed PE, those with TAPSE less than 15mm on FOCUS will have greater overall mortality and need for escalation of care than those with TAPSE greater than 17mm. We will enroll and follow patients diagnosed with acute PE, performing FOCUS with measurement of TAPSE within 6 hours of anticoagulation at academic emergency departments. We hypothesize TAPSE will independently predict outcomes in PE. Quantifiable and reliable measures that improve prognosis of ED patients may allow earlier identification of patients requiring escalation of care.
Drause, Matthew, "Prognostic Utility of Tricuspid Annular Plane Systolic Excursion in Pulmonary Embolism" (2018). Yale School of Medicine Physician Associate Program Theses. 46.
This Article is Open Access