Date of Award


Document Type

Open Access Thesis

Degree Name

Master of Medical Science (MMSc)

First Advisor

E. Jennifer Edelman, MD, MHS


People who inject drugs are at increased risk of acquiring HIV and accounted for 10% of all new diagnoses in 2018. Pre-exposure prophylaxis has been shown to reduce HIV acquisition among at-risk populations, including people who inject drugs. However, pre-exposure prophylaxis is underutilized by people who inject drugs due to limited knowledge about its existence and purpose. The objective of this study is to determine the effectiveness of a patient navigation intervention in increasing initiation of pre-exposure prophylaxis among people who inject drugs. Specifically, we will carry out a randomized controlled study to compare the rates of pre-exposure prophylaxis initiation among individuals receiving an informational pamphlet or a multi-session intervention with a PrEP navigator. The results of this study will serve to determine whether an in-person patient navigation intervention is an effective strategy to improve pre-exposure prophylaxis initiation among people who inject drugs.

Open Access

This Article is Open Access