Platelet Rich Plasma for Women with Recurrent Implantation Failure Undergoing Frozen Embryo Transfer
Date of Award
Summer 7-28-2023
Document Type
Open Access Thesis
Degree Name
Master of Medical Science (MMSc)
First Advisor
Pinar Kodaman, MD, PhD
Abstract
In vitro fertilization with embryo transfer is often considered a solution for infertile women. The proportion of infertile women who fail to become pregnant after an embryo transfer remains high despite advances in assisted reproductive technologies. Use of autologous platelet-rich plasma may have a beneficial effect on implantation. Our objective is to determine if autologous platelet-rich plasma prior to embryo transfer is effective in improving pregnancy rates among women with recurrent implantation failure. We will design a randomized controlled trial such that women will receive an intrauterine infusion of either autologous platelet-rich plasma or saline 48 hours prior to transferring chromosomally normal embryos. Following the embryo transfer, clinical pregnancy rates will be compared between the two groups. These results may provide insight into the effectiveness of autologous platelet-rich plasma on the success rate of embryo transfer in infertile women.
Recommended Citation
Ortiz, Gabriela, "Platelet Rich Plasma for Women with Recurrent Implantation Failure Undergoing Frozen Embryo Transfer" (2023). Yale School of Medicine Physician Associate Program Theses. 230.
https://elischolar.library.yale.edu/ysmpa_theses/230
Comments
This is an open access thesis.