Date of Award
Summer 7-26-2024
Document Type
Open Access Thesis
Degree Name
Master of Medical Science (MMSc)
First Advisor
Vinita Misra Knight, MD, FAES
Abstract
Epilepsy affects about 70 million people worldwide, making it the world’s second most common neurological disease. The first line treatment for epilepsy are anti-seizure medications, but only two-thirds of patients respond to the first two medications given. We propose a randomized controlled study utilizing intermittent fasting as a therapeutic lifestyle modification as an adjuvant to standard drug therapy for those that experience drug-resistant epilepsy. We will assess the efficacy and safety of intermittent fasting for a period of six months, and statistically determine if there is a significant reduction in the mean frequency of seizures participants experience compared to a control group that is treated with standard drug therapy alone. These results will contribute to current research studies suggesting that intermittent fasting may serve as promising new treatment option for those living with drug-resistant epilepsy.
Recommended Citation
Smiech, Jake, "Intermittent Fasting as an Adjuvant to Standard Drug Therapy for Drug Resistant Epilepsy" (2024). Yale School of Medicine Physician Associate Program Theses. 220.
https://elischolar.library.yale.edu/ysmpa_theses/220
Comments
This is an open access thesis.