Date of Award


Document Type

Open Access Thesis

Degree Name

Master of Medical Science (MMSc)

First Advisor

Valentina Ivezaj, PhD


Diagnostic criteria for binge eating disorder may preclude a diagnosis in post-bariatric surgery patients because they require consumption of abnormally large quantities. Loss of control eating is considered the salient feature of binge eating disorder in some eating disorder literature, and some of the field is moving towards excluding the quantity of food criterion. Loss of control eating is associated with poorer weight outcomes post-surgery. Topiramate, an anticonvulsant, has been shown to improve weight outcomes in patients with binge eating disorder after surgery, therefore its evaluation in patients with loss of control eating and obesity post-surgery is warranted. We aim to identify whether topiramate increases weight loss and reduces loss of control eating in patients with obesity and loss of control eating after bariatric surgery via a randomized, double-blind, placebo-controlled trial. This study will enhance our understanding of topiramate for weight loss and loss of control eating in this population.

Available for download on Monday, March 25, 2024

Open Access

This Article is Open Access