Date of Award
4-22-2022
Document Type
Thesis
Degree Name
Master of Medical Science (MMSc)
First Advisor
Craig Canapari, MD
Abstract
Cystic fibrosis is a genetic disease that severely affects lung function and is often comorbid with sleep-disordered breathing. While positive airway pressure therapy is a common treatment for sleep-disordered breathing, it has not been fully evaluated in the cystic fibrosis population for that indication. Additionally, it has mostly been studied in adults, even though the cystic fibrosis population skews younger and poor sleep is detrimental to adolescent development. Therefore, using a prospective cohort study, we will investigate whether high adherence to positive airway pressure therapy improves lung function in adolescent and young adult patients with cystic fibrosis and sleep-disordered breathing more than low adherence to positive airway pressure therapy. Improved lung function will benefit the health-related quality of life in these patients, and positive results from this study could encourage providers to prescribe positive airway pressure therapy more frequently.
Recommended Citation
Bell, Caroline, "Effects of Positive Airway Pressure in Adolescent and Young Adult Patients with Cystic Fibrosis" (2022). Yale School of Medicine Physician Associate Program Theses. 117.
https://elischolar.library.yale.edu/ysmpa_theses/117